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Instinct MI250X 128GB vs RTX 5090

For running local LLMs · 10 reports across 2 models

Side A
Instinct MI250X 128GB
Vendor
amd
VRAM
128GB
Memory
Discrete
Side B
RTX 5090
Vendor
nvidia
VRAM
32GB
Memory
Discrete

Tokens per second by model

ModelInstinct MI250X 128GBRTX 5090
Qwen3.6up to 35B—3238.0n=7
Gemma 4up to 31B—578.0n=3

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